Govindarajan Rajagopalan Selected Research

Type 1 Diabetes Mellitus (Autoimmune Diabetes)

1/2013	Low incidence of spontaneous type 1 diabetes in non-obese diabetic mice raised on gluten-free diets is associated with changes in the intestinal microbiome.
5/2007	Autoimmunity in HLA-DQ8 transgenic mice expressing granulocyte/macrophage-colony stimulating factor in the beta cells of islets of Langerhans.
9/2003	Autoimmune diabetes in HLA-DR3/DQ8 transgenic mice expressing the co-stimulatory molecule B7-1 in the beta cells of islets of Langerhans.
2/2003	Accelerated diabetes in rat insulin promoter-tumor necrosis factor-alpha transgenic nonobese diabetic mice lacking major histocompatibility class II molecules.
11/2002	Modulation of insulitis and type 1 diabetes by transgenic HLA-DR3 and DQ8 in NOD mice lacking endogenous MHC class II.

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Govindarajan Rajagopalan Research Topics

Disease

13	Septic Shock (Toxic Shock Syndrome) 01/2020 - 11/2004
7	Infections 01/2024 - 10/2006
6	Inflammation (Inflammations) 10/2018 - 02/2006
5	Autoimmune Diseases (Autoimmune Disease) 10/2018 - 04/2006
5	Pneumonia (Pneumonitis) 10/2017 - 06/2012
5	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2013 - 11/2002
5	Shock 06/2012 - 07/2002
3	Systemic Lupus Erythematosus (Libman-Sacks Disease) 11/2015 - 11/2011
3	Genetic Predisposition to Disease (Genetic Predisposition) 11/2015 - 01/2008
2	Lung Injury 01/2023 - 01/2022
2	Bacteremia 08/2019 - 08/2015
2	Neoplasms (Cancer) 01/2018 - 06/2010
2	Foodborne Diseases 06/2010 - 12/2008
1	Bacterial Infections (Bacterial Infection) 01/2024
1	Pseudomonas Infections 04/2023
1	Hyperoxia 01/2022
1	Cytokine Release Syndrome 01/2020
1	COVID-19 01/2020
1	Immunoglobulin G4-Related Disease 10/2018
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 05/2017
1	Wound Infection (Wound Infections) 12/2015
1	Wounds and Injuries (Trauma) 12/2015
1	Glomerulonephritis 11/2015
1	Lupus Nephritis 11/2015
1	Melanoma (Melanoma, Malignant) 10/2015
1	Neoplasm Metastasis (Metastasis) 10/2015
1	Endocarditis 06/2014
1	Hyperglycemia 01/2013
1	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 06/2012
1	Sialadenitis 05/2007
1	Colitis 04/2006

Drug/Important Bio-Agent (IBA)

19	SuperantigensIBA 01/2020 - 11/2004
9	HLA-DR3 Antigen (HLA DR3 Antigen)IBA 10/2017 - 11/2002
8	staphylococcal enterotoxin BIBA 01/2021 - 11/2004
6	CytokinesIBA 06/2012 - 11/2004
5	HLA-DQ8 antigenIBA 01/2014 - 07/2002
4	ExotoxinsIBA 12/2015 - 02/2007
4	HLA Antigens (Human Leukocyte Antigens)IBA 10/2012 - 11/2002
3	AntibodiesIBA 01/2020 - 01/2011
2	Interleukin-17 (Interleukin 17)IBA 01/2023 - 01/2020
2	InterferonsIBA 01/2020 - 02/2011
2	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2018 - 05/2017
2	Linezolid (Zyvox)FDA Link 10/2017 - 10/2012
2	Peptides (Polypeptides)IBA 10/2015 - 11/2004
2	Enterotoxins (Enterotoxin)IBA 06/2014 - 06/2012
1	Investigational DrugsIBA 01/2024
1	Anti-Bacterial Agents (Antibiotics)IBA 04/2023
1	PorphyrinsIBA 04/2023
1	ZincIBA 04/2023
1	Oxygen (Dioxygen)IBA 01/2022
1	ErbB Receptors (EGF Receptor)IBA 01/2022
1	Janus Kinase InhibitorsIBA 01/2020
1	Chimeric Antigen ReceptorsIBA 01/2020
1	Rituximab (Mabthera)FDA Link 10/2018
1	AutoantibodiesIBA 10/2018
1	AutoantigensIBA 10/2018
1	SteroidsIBA 10/2018
1	TNF-Related Apoptosis-Inducing LigandIBA 01/2018
1	Immunoglobulin Fc FragmentsIBA 10/2017
1	Immunoglobulin G (IgG)IBA 10/2017
1	Bacterial Proteins (Bacterial Protein)IBA 10/2017
1	Formoterol Fumarate (Oxis)FDA Link 05/2017
1	Budesonide (Pulmicort)FDA LinkGeneric 05/2017
1	2,6-dinitrotoluene (DNT)IBA 01/2017
1	HLA-DR2 Antigen (HLA DR2 Antigen)IBA 11/2015
1	AntigensIBA 10/2015
1	ImmunosorbentsIBA 06/2014
1	EnzymesIBA 06/2014
1	Staphylococcal enterotoxin FIBA 06/2014
1	lipoteichoic acidIBA 01/2014
1	Lipoproteins (Lipoprotein)IBA 01/2014
1	Peptidoglycan (Murein)IBA 01/2014
1	Pathogen-Associated Molecular Pattern MoleculesIBA 01/2014
1	Caseins (Casein)FDA Link 01/2013
1	Glutens (Glutelin)IBA 01/2013
1	Vancomycin FDA LinkGeneric 10/2012
1	ChemokinesIBA 06/2012
1	Immunosuppressive Agents (Immunosuppressants)IBA 06/2012
1	Tacrolimus (Prograf)FDA LinkGeneric 06/2012
1	HLA-D AntigensIBA 11/2011
1	Interferon-gamma (Interferon, gamma)IBA 02/2011
1	Bortezomib (Velcade)FDA Link 06/2010
1	Biological Warfare AgentsIBA 06/2010
1	LipopolysaccharidesIBA 06/2010
1	NF-kappa B (NF-kB)IBA 06/2010
1	Proteasome InhibitorsIBA 06/2010
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 12/2008
1	HLA-DR Antigens (HLA-DR)IBA 01/2008
1	Histocompatibility Antigens Class IIIBA 05/2007
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 05/2007
1	Intravenous Immunoglobulins (IVIG)FDA Link 01/2007
1	Freund's AdjuvantIBA 04/2006

Therapy/Procedure

5	Therapeutics 01/2024 - 06/2012
1	Phage Therapy 01/2024
1	Artificial Respiration (Mechanical Ventilation) 05/2017
1	Immunotherapy 10/2015
1	Catheters 08/2015
1	Gluten-Free Diet 01/2013
1	Drug Therapy (Chemotherapy) 06/2010
1	Intravaginal Administration 02/2007